Phospho-Src (Ser17) (D7F2Q) Rabbit mAb 12432S from Cell Signaling Technology

Product Specs
ItemPhospho-Src (Ser17) (D7F2Q) Rabbit mAb
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number12432S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
ClonalityMonoclonal
TargetSrc (Ser17) phosphate
HostRabbit
NCBI Full Gene NameSRC proto-oncogene, non-receptor tyrosine kinase
NCBI Gene AliasesASV, SRC1, THC6, c-SRC, p60-Src
ModificationsSrc (Ser17) phosphate
Research AreaMAP Kinase Signaling
CloneD7F2Q
Molecular Weight60

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Small‐molecule nanoprodrug with high drug loading and EGFR, PI3K/AKT dual‐inhibiting properties for bladder cancer treatmentExploration (Beijing)October 1, 2023Guoyin Li, Zewen Song, Yi Ru, Jing Zhang, Lianxiang Luo, Wei Yang, Hao Wu, Haibao Jin, Xuanwen Bao, Di Wei, et al.Phospho‐PI3K (AF3242, affinity), BCL2 (ab692, Abcam), BAX (ab53154, Abcam), SRC (#2019, CST), Phospho‐SRC (#12432, CST), and GAPDH (#2118, CST). 2.11 Immunohistochemistry and immunocytochemistry The immunohistochemical

(2) Antimetastatic activity of seongsanamide B in γ-irradiated human lung cancerHeliyonSeptember 14, 2023Ga-Hee Ryoo, Geum Jin Kim, Ah-Reum Han, Chang Hyun Jin, Hunmin Lee, Joo-Won Nam, Hyukjae Choi, Chan-Hun Jungprimary antibodies against β-catenin (#8480), p-STAT3 (#9145), STAT3 (#9139), Bcl-XL (#2762), p-Src (#12432), Src (#2109), SOD2 (#13141), E-cadherin (#14472), vimentin (#5741) (Cell Signaling Technology, Danvers,

(3) The anti-oncogenic effect of 17-DMAG via the inactivation of HSP90 and MET pathway in osteosarcoma cellsOncology ResearchJuly 21, 2023MASANORI KAWANO, KAZUHIRO TANAKA, ICHIRO ITONAGA, TATSUYA IWASAKI, YUTA KUBOTA, HIROSHI TSUMURACaspase 8 (#4790), Cleaved caspase 8 (#9496), RhoA (#2117), ROCK (#4035), Src (#2109), p-Src (S17)(#12432), FAK (#3285), p-FAK (Y397)(#8556), Paxillin (#12065), p-Paxillin (Y118) (#69363), and GAPDH (#5174);

(4) Lanosterol synthase loss of function decreases the malignant phenotypes of HepG2 cells by deactivating the Src/MAPK signaling pathwayOncology lettersJuly 1, 2023Sun X, Zhang J, Liu H, Li M, Liu L, Yang Z, Hu W, Bai H, Xu J, Xing J, et al.ab32536, 1:500, Abcam, Cambridge, UK; endocan, cat. no. sc-515304, 1:300, Santa Cruz, CA; pSrc, cat. no. 12432S, 1:500, Cell Signaling Technology, Danvers, MA; Src, cat. no. 2109S, 1:500, Cell Signaling Technology,

(5) TRPM7 kinase mediates hypomagnesemia-induced seizure-related deathScientific reportsMay 15, 2023Liu M, Liu H, Feng F, Krook-Magnuson E, Dudley SC.(ThermoFisher Scientific PA5-53286), anti-SLC41A3 (Novus Bio NBP1-59764), and anti-p-Src Ser17 (Cell Signaling 12432). Horseradish peroxidase-conjugated goat anti-rabbit and anti-mouse IgG secondary antibodies (Bio-Rad,

(6) Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H(2)O(2)-Induced Oxidative Injury via the IL-6/Nrf2 Loop PathwayAntioxidants (Basel, Switzerland)October 12, 2022Xiong L, Wu H, Zhong T, Luo F, Li Q, Li M, Fan Y.blots (Bio-Rad, Hercules, CA, USA). p-SAPK/JNK (Thr183/Tyr185; #4685), SAPK/JNK (#9252), p-Src (Ser17; #12432), p-Stat3 (Tyr705; #9145), mTOR (2065AP), p-mTOR (Ser2448; #5536), p-Akt (Ser473; #4060), p-GSK3β (Ser9;

(7) ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathwayJournal of Experimental & Clinical Cancer ResearchDecember 1, 2021Hongyu Li et al.#9661), ITGA10 (SAB; #44824), PAK (CST; #2602), p-PAK (CST; #2606), p-FAK (CST; #8556), p-SRC (CST; #12432), CREB (CST; #12432), and p-CREB (CST; #9198) overnight at 4 °C. The membranes were then washed in TBST,

(8) BACE1 controls synaptic function through modulating release of synaptic vesiclesMolecular psychiatryNovember 1, 2021Das B, Singh N, Yao AY, Zhou J, He W, Hu X, Yan R.Cell Signaling #3291]; Src [1:1000, Cell Signaling #2123]; p-Src (D7F2Q) [1:1000, Cell Signaling # 12432]; NMDAR1 [1:250, Chemicon AB1516]; NMDAR2B (D15B3) [1:1000, Cell Signaling #4212]; p-NMDAR-2B (Ser1284)

(9) Proteomic Analysis of Src Family Kinase Phosphorylation States in Cancer Cells Suggests Deregulation of the Unique DomainMolecular cancer research : MCRJune 1, 2021Ruiz-Saenz A, Zahedi F, Peterson E, Yoo A, Dreyer CA, Spassov DS, Oses-Prieto J, Burlingame A, Moasser MM.non-pY416-SFK (Cell Signaling cs-2102), non-pY527-SFK (Cell Signaling cs-2107), pS17-Src (Cell Signaling 12432s), Src (Cell Signaling 2110s), HA (SantaCruz Biotech sc-7392 and Cell Signaling cs-3724), Flag (Cell Signaling

(10) Protein kinase A inhibitor proteins (PKIs) divert GPCR-Gαs-cAMP signaling toward EPAC and ERK activation and are involved in tumor growthFASEB journal : official publication of the Federation of American Societies for Experimental BiologyOctober 1, 2020Hoy JJ, Salinas Parra N, Park J, Kuhn S, Iglesias-Bartolome R.USA], catalog no. 2101; 1:1000), anti-phospho-Src (S17) (Cell Signaling [Danvers, MA, USA], catalog no. 12432; 1:1000), anti-Src (Cell Signaling [Danvers, MA, USA], catalog no. 2109; 1:1000), anti-phospho-c-Raf

(11) The eEF2 kinase-induced STAT3 inactivation inhibits lung cancer cell proliferation by phosphorylation of PKM2Cell communication and signaling : CCSFebruary 13, 2020Xiao M, Xie J, Wu Y, Wang G, Qi X, Liu Z, Wang Y, Wang X, Hoque A, Oakhill J, et al.(#74129), JAK2 (#3230), p-JAK2 (#3771), p-PI3K (#4228), AKT (#4685), p-AKT (#9614), Src (#12109), p-Src (#12432), STAT3 (#12640), p-STAT3 (#9145), eEF2K (#3692), eEF2 (#2332), p-eEF2 (#2331), c-Myc(#2729), and PKM2

(12) TOPK promotes metastasis of esophageal squamous cell carcinoma by activating the Src/GSK3β/STAT3 signaling pathway via γ-cateninBMC cancerDecember 30, 2019Jiang Y, Zhang J, Zhao J, Li Z, Chen H, Qiao Y, Chen X, Liu K, Dong Z.Cell Signaling Technology: anti-Stat3 (#9139), anti-p-Stat3 (#9145), anti-Src (#2109), anti-p-Src (#12432), anti-Erk (#4696), anti-p-Erk (#4370), anti-GSK3β (#5676), and anti-p-GSK3β (#9327) antibodies. The

(13) MPZL1 promotes tumor cell proliferation and migration via activation of Src kinase in ovarian cancerOncology reportsAugust 1, 2019Chen D, Cao L, Wang X.4015), cortactin (cat. no. 3502), p-cortactin (cat. no. 4569), Src (cat. no. 2108), p-Src (cat. no. 12432), MPZL1 (cat. no. 9893) and GAPDH (cat. no. 5174) (all Cell Signaling Technology, Inc). Notably, since

(14) MicroRNA‑195 is associated with regulating the pathophysiologic process of human laryngeal squamous cell carcinomaMolecular medicine reportsApril 1, 2018Pang H, Xu X, Dai L, Wang K, Yao X.kinase kinase (MEK; 601121, 1:200), and p‑MEK (558375, 1:1,000) (both from BD Biosciences), p‑SRC (12432; 1:1,000), focal adhesion kinase (FAK; 3285; 1:1,000), p‑FAK (8556; 1:1,000) (all from Cell Signaling Technology

(15) SLIT2/ROBO1 axis contributes to the Warburg effect in osteosarcoma through activation of SRC/ERK/c-MYC/PFKFB2 pathwayCell death & diseaseMarch 9, 2018Zhao SJ, Shen YF, Li Q, He YJ, Zhang YK, Hu LP, Jiang YQ, Xu NW, Wang YJ, Li J, et al.Cambridge, UK), SLIT2 (ab134166; Abcam), SRC (2109; Cell Signaling Technology, Danvers, MA, USA), p-Src (12432; Cell Signaling Technology), extracellular signal-regulated kinase (ERK, 4695; Cell Signaling Technology),

(16) EDIL3 knockdown inhibits retinal angiogenesis through the induction of cell cycle arrest in vitroMolecular medicine reportsOctober 1, 2017Shen W, Zhu S, Qin H, Zhong M, Wu J, Zhang R, Song H.(Catalog: 4370), EGFR (Catalog: 2085), p-EGFR (Catalog: 2244), Src (Catalog: 2109) and p-Src (Catalog: 12432) were purchased from CST Biological Reagents Company Limited (Shanghai, China). Propidium iodide (PI)/RNase Staining Solution

(17) Crk-like adapter protein is overexpressed in cervical carcinoma, facilitates proliferation, invasion and chemoresistance, and regulates Src and Akt signalingOncology LettersNovember 1, 2016Hong Ji, Bo Li, Shitai Zhang, Zheng He, Yang Zhou, Ling Ouyangdilution, 1:1,000; cat. no. ABC242; EMD Millipore), p-Src (rabbit monoclonal; dilution, 1:1,000; cat. no. 12432; Cell Signaling Technology, Inc., Boston, MA, USA), Src (rabbit monoclonal; dilution, 1:1,000; cat.

(18) Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound BerberineInternational Journal of Molecular SciencesApril 16, 2016Xuanbin Wang, Ning Wang, Hongliang Li, Ming Liu, Fengjun Cao, Xianjun Yu, Jingxuan Zhang, Yan Tan, Longchao Xiang, Yibin Feng(#11907S), p-p38 (#4511), p38 (#8690), p-Erk1/2 (#4370), Erk1/2 (#4695), p-JNK/SAPK (#9255), p-Src (#12432), Src (#2108), HMGB1 (#6893S), NF-κB (#3033, #8242), TIMP-1 (#8946), MMP-9 (#3852S), MMP-2 (#4022S)

(19) Secreted protein acidic and rich in cysteine antagonizes bufalin-induced apoptosis in gastric cancer cellsMolecular Medicine ReportsAugust 1, 2015AODI LI, XIUJUAN QU, ZHI LI, JINGLEI QU, NA SONG, YANJU MA, YUNPENG LIU(ERK; cat. no. 4348; 1:1,000) anti‑phospho‑ERK (cat. no. 4370; 1:2,000), anti‑phospho‑Src (cat. no. 12432; 1:1,000), anti‑poly(ADP‑ribose) polymerase (PARP; cat. no. 5625, 1:1,000) and anti‑Bcl‑2 (cat. no.

Be the First to Write a Review!

Phospho-Src (Ser17) (D7F2Q) Rabbit mAb

Phospho-Src (Ser17) (D7F2Q) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (19)

Reviews

Phospho-Src (Ser17) (D7F2Q) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map